The hallmark of this new century has been one of disruption. Dynamic change no longer comes in the form of incremental process. New ideas and technologies emerge every day, threatening existing systems and our entire economic structure, while simultaneously creating new opportunities. For those who thought the rise of automation and globalization of the past century were difficult to weather, the near future looks to be even more turbulent. As we endure the frenetic pace of change happening in many aspects of life, we experience impatience in areas where it is not. Right now there are innovators, idealists and entrepreneurs with the courage to rethink every facet of our world. Education, transportation, healthcare, finance and agriculture, all cornerstones of the Iowa City area economy, are in the crosshairs for these disruptors.